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Literature ReviewHighlighted

A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives

MHID-0845802PMID: 399115282025Biochemistry and Biophysics Reports

Fatmanur Yıldız, Tyler W. LeBaron, Duried Alwazeer

Oxidative stress is responsible for the pathogenesis of many diseases, and antioxidants are commonly included in their treatment protocols. Over the past two decades, numerous biomedical reports have revealed the therapeutic benefits of molecular hydrogen (H2) in relieving oxidation-related diseases. H2 has been found to have selective antioxidant properties against the most dangerous oxidants (hy

Animal StudyHighlighted

Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model

MHID-2919108PMID: 349481072021International Journal of Molecular Sciences

Eun-Sook Jeong, Johny Bajgai, In-Soo You, Md. Habibur Rahman, Ailyn Fadriquela, Subham Sharma, et al.

Oxidative stress (OS) is one of the causative factors in the pathogenesis of various neurode- generative diseases, including Alzheimer’s disease (AD) and cognitive dysfunction. In the present study, we investigated the effects of hydrogen (H2) gas inhalation in trimethyltin (TMT)-induced neurotoxicity and cognitive dysfunction in the C57BL/6 mice. First, mice were divided into the following groups

Clinical TrialAnimal StudyHighlighted

Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome

MHID-5560534PMID: 236101592013Journal of Lipid Research

Guohua Song, Min Li, Hui Sang, Liying Zhang, Xiuhong Li, Shutong Yao, et al.

We have found that hydrogen (dihydrogen; H 2 ) has benefi cial lipid-lowering effects in high-fat diet-fed Syrian golden hamsters. The objective of this study was to characterize the effects of H 2 -rich water (0.9–1.0 l/day) on the content, composition, and biological activities of serum lipoproteins on 20 patients with potential metabolic syn- drome. Serum analysis showed that consumption of H 2