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Animal StudyIn VitroHighlighted

Long-term administration of hydrogen-rich water enhances quality of life in diabetic rats and reduces renal neoplasm incidence through modulation of inflammatory and metabolic pathways

MHID-4061148PMID: 406876592025Translational Andrology and Urology

Qijie Chen, Shaoqing Yu, Yating Pan, Hong Tang, Yang Wang, Ninghan Feng, et al.

Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, leading to severe systemic complications and reduced quality of life. Current therapies often fail to comprehensively alleviate diabetic complications, highlighting the need for novel approaches. Animal studies and clinical trials have demonstrated the therapeutic potential of molecular hy

Animal StudyHighlighted

Effects of long‑term hydrogen intervention on the physiological function of rats

MHID-8428241PMID: 331161632020Scientific Reports

Zhi‑ming Xun, Qing‑hui Zhao, Yan Zhang, Fang‑di Ju, Jin He, Ting‑ting Yao, et al.

The potential therapeutic effects of molecular hydrogen (H2) have now been confirmed in various human and animal-disease models. However, the effects of H2 on the physiological function in a normal state have been largely neglected. Hydrogen-rich water (HRW) intake and hydrogen inhalation (HI) are the most common used methods for hydrogen administration, the difference in the effects between HRW i

Animal StudyHighlighted

Anti-obesity Effect of Alkaline Reduced Water in High Fat-Fed Obese Mice

MHID-3385882PMID: 238115542013Biological & Pharmaceutical Bulletin

Rosa Mistica Coles Ignacio, Tae-Young Kang, Cheol-Su Kim, Soo-Ki Kim, Young-Chul Yang, Joon-Hyung Sohn, et al.

Whether or not alkaline reduced water (ARW) has a positive effect on obesity is unclear. This study aims to prove the positive effect of ARW in high-fat (HF) diet-induced obesity (DIO) in C57BL/6 mice model. Toward this, obesity was induced by feeding the C57BL/6 male mice with high-fat diet (w/w 45% fat) for 12 weeks. Thereafter, the animals were administered with either ARW or tap water. Next, t