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Animal StudyHighlighted

An ethically guided preclinical device for phenotyping H2 production in laboratory rodents

MHID-9069735PMID: 389256262024Animal Models and Experimental Medicine

Victor Pascal-Moussellard, Emilie Boucher, Stéphane Tanguy, Philippe Cinquin, Pierre-Alain Barraud, Chloé Davin, et al.

Background: Dihydrogen (H2) is produced endogenously by the intestinal microbiota through the fermentation of diet carbohydrates. Over the past few years, numerous studies have demonstrated the significant therapeutic potential of H2 in various pathophysiological contexts, making the characterization of its production in laboratory species of major preclinical importance. Methods: This study prop