Animal StudyHighlighted
MHID-8252742PMID: 395944702024Antioxidants
Wenjing He, Md. Habibur Rahman, Johny Bajgai, Sofian Abdul-Nasir, Chaodeng Mo, Hui Ma, et al.
Airway inflammatory diseases, such as asthma, are a global public health concern owing to their chronic inflammatory effects on the respiratory mucosa. Molecular hydrogen (H2) has recently been recognized for its antioxidant and anti-inflammatory properties. In this study, we examined the therapeutic potential of H2 in airway inflammation using an ovalbumin (OVA)-induced BALB/c mouse model of alle
Clinical TrialHighlighted
MHID-68343622020临床耳鼻咽喉头颈外科杂志 (J Clin Otorhinolaryngol Head Neck Surg (China))
金玲, 范锴, 张熙, 赵义华, 葛琴, 王扬, et al.
Objective: To observe the effect of hydrogen-rich saline on the concentration of nitric oxide in the nose, and to explore the mechanism of its treatment of allergic rhinitis. Method: Twenty patients with moderate to severe persistent allergic rhinitis were enrolled in a randomized, double-blind, self-controlled study. The nasal cavity was lavaged with hydrogen-rich normal saline and normal saline,
Animal StudyHighlighted
MHID-5043020PMID: 236615162013European Review for Medical and Pharmacological Sciences
M. Xiao, T. Zhu, T. Wang, F.-Q. Wen
Recent studies suggest that hydrogen has great therapeutic and prophylactic potential against organ injury caused by oxidative stress and inflammation. Here we investigated the effect of hydrogen-rich saline on airway inflammation and remodeling in a murine model of asthma.
MATERIALS AND METHODS: Asthma was induced by ovalbumin (OVA) sensitization and challenge. Then mice were treated with normal