In VitroChemical/Physicochemical StudyHighlighted
MHID-6183029PMID: 267392572016Scientific Reports
Katsuya Iuchi, Akemi Imoto, Naomi Kamimura, Kiyomi Nishimaki, Harumi Ichimiya, Takashi Yokota, et al.
We previously showed that H2 acts as a novel antioxidant to protect cells against oxidative stress. Subsequently, numerous studies have indicated the potential applications of H2 in therapeutic and preventive medicine. Moreover, H2 regulates various signal transduction pathways and the expression of many genes. However, the primary targets of H2 in the signal transduction pathways are unknown. Her
Animal StudyIn VitroHighlighted
MHID-7164222PMID: 227767732012Medical Gas Research
Masanori Katakura, Michio Hashimoto, Yoko Tanabe, Osamu Shido
Background: Reactive oxygen species (ROS) production induced by α,β-dicarbonyl compounds and advanced glycation end products causes renal dysfunction in patients with type 2 diabetes and metabolic syndrome. Hydrogen-rich water (HRW) increases the H2 level in blood and tissues, thus reducing oxidative stress in animals as well as humans. In this study, we investigated the effects of HRW on glucose-
Animal StudyHighlighted
MHID-2283082PMID: 115104172001Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie / Life Sciences (Comptes Rendus Biologies)
Bouchra Gharib, Stéphane Hanna, Ould M.S. Abdallahi, Hubert Lepidi, Bernard Gardette, Max De Reggi
Molecular hydrogen reacts with the hydroxyl radical, a highly cytotoxic species produced in inflamed tissues. It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy. We tested this idea, with the aid of the equipment and skills of COMEX SA in Marseille, a group who experiments with oxygen–hydrogen breathing mixtures for professional deep-sea diving. The model use
