Clinical TrialHighlighted
MHID-7707676PMID: 375698502023International Journal of Molecular Sciences
Zuzana Sumbalova, Jarmila Kucharská, Zuzana Rausová, Anna Gvozdjakova, Mária Szántová, Branislav Kura, et al.
Molecular hydrogen (H2) has been recognized as a novel medical gas with antioxidant and anti-inflammatory effects. Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increased fat accumulation in liver tissue caused by factors other than alcohol consumption. Platelet mitochondrial function is considered to reflect systemic mitochondrial health. We studied the ef- fect of adjuvant th
Animal StudyHighlighted
MHID-7644453PMID: 277741162016Oxidative Medicine and Cellular Longevity
Jiaming Guo, Deyun Zhao, Xiao Lei, Hainan Zhao, Yanyong Yang, Pei Zhang, et al.
Molecular hydrogen (H2) has been previously reported playing an important role in ameliorating damage caused by acute radiation. In this study, we investigated the effects of H2 on the alterations induced by low-dose long-term radiation (LDLTR). All the mice in hydrogen-treated or radiation-only groups received 0.1 Gy, 0.5 Gy, 1.0 Gy, and 2.0 Gy whole-body gamma radiation, respectively. After the
Animal StudyHighlighted
MHID-1117942PMID: 251770312014Biological & Pharmaceutical Bulletin
Yang-Suk Yoon, Ma. Easter Joy Villarosa Sajo, Rosa Mistica Coles Ignacio, Soo-Ki Kim, Cheol-Su Kim, Kyu-Jae Lee
Atopic dermatitis (AD) is a chronically relapsing, pruritic, eczematous skin disorder accompanying al- lergic inflammation. AD is triggered by oxidative stress and immune imbalance. In the present study, we in- vestigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that HW ameliorated DNCB-induced AD-like clinical
Animal StudyHighlighted
MHID-3385882PMID: 238115542013Biological & Pharmaceutical Bulletin
Rosa Mistica Coles Ignacio, Tae-Young Kang, Cheol-Su Kim, Soo-Ki Kim, Young-Chul Yang, Joon-Hyung Sohn, et al.
Whether or not alkaline reduced water (ARW) has a positive effect on obesity is unclear. This study aims to prove the positive effect of ARW in high-fat (HF) diet-induced obesity (DIO) in C57BL/6 mice model. Toward this, obesity was induced by feeding the C57BL/6 male mice with high-fat diet (w/w 45% fat) for 12 weeks. Thereafter, the animals were administered with either ARW or tap water. Next, t
Animal StudyHighlighted
MHID-2488306PMID: 220408782011Biological & Pharmaceutical Bulletin
Kyung Su YOON, Xue Zhu HUANG, Yang Suk YOON, Soo-Ki Kim, Soon Bong SONG, Byung Soo CHANG, et al.
Electrolyzed reduced water (ERW), functional water, has various beneficial effects via antioxidant mecha-
nism in vivo and in vitro. However there is no study about beneficial effects of ERW bathing. This study aimed to
determine the effect of ERW bathing on the UVB-induced skin injury in hairless mice. For this purpose, mice
were irradiated with UVB to cause skin injury, followed by individually ta
