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Animal Study

Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease

MHID-4869388PMID: 316002562019PLoS ONE

Laura Bordoni, Rosita Gabbianelli, Donatella Fedeli, Dennis Fiorini, Ina Bergheim, Cheng Jun Jin, et al.

There is growing awareness within the scientific community of the strong connection between the inflammation in the intestine and the pathogenesis of Parkinson’s disease (PD). In previous studies we developed a PD animal model exposing pup rats to permethrin (PERM) pesticide. Here, we intended to explore whether in our animal model there were changes in gut permeability, fecal microbiota and hepat

Animal StudyHighlighted

Anti-obesity Effect of Alkaline Reduced Water in High Fat-Fed Obese Mice

MHID-3385882PMID: 238115542013Biological & Pharmaceutical Bulletin

Rosa Mistica Coles Ignacio, Tae-Young Kang, Cheol-Su Kim, Soo-Ki Kim, Young-Chul Yang, Joon-Hyung Sohn, et al.

Whether or not alkaline reduced water (ARW) has a positive effect on obesity is unclear. This study aims to prove the positive effect of ARW in high-fat (HF) diet-induced obesity (DIO) in C57BL/6 mice model. Toward this, obesity was induced by feeding the C57BL/6 male mice with high-fat diet (w/w 45% fat) for 12 weeks. Thereafter, the animals were administered with either ARW or tap water. Next, t

Animal StudyHighlighted

Histological Study on the Effect of Electrolyzed Reduced Water-Bathing on UVB Radiation-Induced Skin Injury in Hairless Mice

MHID-2488306PMID: 220408782011Biological & Pharmaceutical Bulletin

Kyung Su YOON, Xue Zhu HUANG, Yang Suk YOON, Soo-Ki Kim, Soon Bong SONG, Byung Soo CHANG, et al.

Electrolyzed reduced water (ERW), functional water, has various beneficial effects via antioxidant mecha- nism in vivo and in vitro. However there is no study about beneficial effects of ERW bathing. This study aimed to determine the effect of ERW bathing on the UVB-induced skin injury in hairless mice. For this purpose, mice were irradiated with UVB to cause skin injury, followed by individually ta