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Literature ReviewHighlighted

Molecular Hydrogen in the Treatment of Respiratory Diseases

MHID-45792272025International Journal of Molecular Sciences

Dominika Zajac, Monika Jampolska, Piotr Wojciechowski

Molecular hydrogen is gaining increasing attention as an antioxidant, anti- inflammatory, and antiapoptotic agent. Once considered an inert gas, it reveals current therapeutic potential among others in inflammatory diseases, cancer, and sports medicine, among others. The present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in

Animal Study

Effect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: an in-vivo study

MHID-3239928PMID: 386383342024Frontiers in Pharmacology

Weiming Yan, Qiurui He, Pan Long, Tao Chen, Lei Zhang, Haiyan Wang

Objective Our research was performed in order to explore the effects of molecular hydrogen (H2), a novely-established antioxidant, on the retinal degeneration in rd1 mice, an animal model of inherited retinitis pigmentosa (RP). Methods The rd1 mice were divided randomly into control and H2 intervention groups. Mice from other groups received H2 intervention in three modes, two modes of the hydrog

Animal StudyIn VitroHighlighted

Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling

MHID-2423362PMID: 334391022021American Journal of Physiology - Gastrointestinal and Liver Physiology

Shao-Wei Li, Terumi Takahara, Weitao Que, Masayuki Fujino, Wen-Zhi Guo, Shin-ichi Hirano, et al.

Nonalcoholic steatohepatitis (NASH) could progress to hepatic fibrosis in the absence of effective control. The purpose of our experiment was to investigate the protective effect of drinking water with a high concentration of hydrogen, namely, hydrogen-rich water (HRW), on mice with nonalcoholic fatty liver disease to elucidate the mechanism underlying the therapeutic action of molecular hydrogen.