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Animal Study

Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent

MHID-1878579PMID: 322460952020Scientific Reports

Yuki Kobayashi, Ryoichi Imamura, Yoshihisa Koyama, Makoto Kondo, Hikaru Kobayashi, Norio Nonomura, et al.

We have developed Si-based agent which can generate a large amount of hydrogen. Si-based agent continues generating hydrogen for more than 24 h by the reaction with water under conditions similar to those in bowels, i.e., pH8.3 and 36 °C, and generates ~400 mL hydrogen. To investigate beneficial effects for diseases associated with oxidative stress, Si-based agent is administered to remnant kidney