Systematic ReviewHighlightedEffect of hydrogen-rich water on periodontal disease, interleukin and blood glucose levels in diabetic: a systematic reviewMHID-30922442021Journal of Syiah Kuala Dentistry SocietyAlbert Manggading Hutapea, Lina HadiDiabetes Mellitus (DM) is a metabolic disorder characterized by high blood glucose levels associated with periodontal disease and increased levels of inflammatory biomarkers such as interleukin. Therapeutic effects of molecular hydrogen for a wide range of disease models and human diseases have been investigated. This review aims to systematically analyze and review animal and human studies invest