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Systematic ReviewMeta-Analysis

Can molecular hydrogen supplementation reduce exercise-induced oxidative stress in healthy adults? A systematic review and meta-analysis

MHID-0733746PMID: 385908282024Frontiers in Nutrition

Yiting Li, Renjie Bing, Meng Liu, Zhangyuting Shang, Yan Huang, Kaixiang Zhou, et al.

Objective: Exercise-induced oxidative stress affects multiple neurophysiological processes, diminishing the exercise performance. Hydrogen (H2) can selectively reduce excessive free radicals, but studies observed its “dual effects” on exercise-induced oxidative stress, that is, increasing or decreasing the oxidative stress. Therefore, we here conducted a systematic review and meta-analysis to quan

Literature Review

Application of Molecular Hydrogen as a Novel Antioxidant in Sports Science

MHID-9675573PMID: 320157862020Oxidative Medicine and Cellular Longevity

Takuji Kawamura, Kazuhiko Higashida, Isao Muraoka

Molecular hydrogen (H2) is a colorless, tasteless, odorless, and minimal molecule with high flammability. Although H2 has been thought to be an inert gas in living bodies for many years, an animal study reported that inhalation of H2 gas decreased oxidative stress and suppressed brain injury caused by ischemia and reperfusion injury due to its antioxidant action. Since then, the antioxidant action

Literature Review

Hydrogen gas: from clinical medicine to an emerging ergogenic molecule for sports athletes

MHID-3461972PMID: 309702152019Canadian Journal of Physiology and Pharmacology

Tyler W. LeBaron, Ismail Laher, Branislav Kura, Jan Slezak

H2 has been clinically demonstrated to provide antioxidant and anti-inflammatory effects, which makes it an attractive agent in exercise medicine. Although exercise provides a multiplicity of benefits including decreased risk of disease, it can also have detrimental effects. For example, chronic high-intensity exercise in elite athletes, or sporadic bouts of exercise (i.e. noxious exercise) in unt

Literature Review

Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

MHID-7427440PMID: 255259532015International Journal of Sports Medicine

S. M. Ostojic

In the past 2 decades, molecular hydrogen emerged as a novel therapeutic agent, with anti-oxidant, anti-inflammatory and anti-apoptotic effects demonstrated in plethora of animal disease models and human studies. Beneficial effects of molecular hydrogen in clinical environment are observed especially in oxidative stress-mediated diseases, such as diabetes mellitus, brain stem infarction, rheumatoi