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Literature Review

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

MHID-1191317PMID: 406196052025Advanced Science

Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, et al.

The delivery of molecular hydrogen (H2) is increasingly recognized for its potential in precision immunomodulation, primarily through multiple pathways such as antioxidant action, modulation of inflammatory factors, and inhibition of apoptosis. These effects contribute to a balanced and functional immune system, highlighting the therapeutic promise of H2 in various inflammatory conditions. However, t

Literature Review

Hydrogen gas: from clinical medicine to an emerging ergogenic molecule for sports athletes

MHID-3461972PMID: 309702152019Canadian Journal of Physiology and Pharmacology

Tyler W. LeBaron, Ismail Laher, Branislav Kura, Jan Slezak

H2 has been clinically demonstrated to provide antioxidant and anti-inflammatory effects, which makes it an attractive agent in exercise medicine. Although exercise provides a multiplicity of benefits including decreased risk of disease, it can also have detrimental effects. For example, chronic high-intensity exercise in elite athletes, or sporadic bouts of exercise (i.e. noxious exercise) in unt

Literature Review

The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance

MHID-0878205PMID: 236800322013Medical Gas Research

Brandon J Dixon, Jiping Tang, John H Zhang

Studies on molecular hydrogen have evolved tremendously from its humble beginnings and have continued to change throughout the years. Hydrogen is extremely unique since it has the capability to act at the cellular level. Hydrogen is qualified to cross the blood brain barrier, to enter the mitochondria, and even has the ability to translocate to the nucleus under certain conditions. Once in these i