Clinical TrialHighlighted鼻呼出一氧化氮在富氢盐水灌洗鼻腔治疗变应性鼻炎中的变化及意义MHID-68343622020临床耳鼻咽喉头颈外科杂志 (J Clin Otorhinolaryngol Head Neck Surg (China))金玲, 范锴, 张熙, 赵义华, 葛琴, 王扬, et al.Objective: To observe the effect of hydrogen-rich saline on the concentration of nitric oxide in the nose, and to explore the mechanism of its treatment of allergic rhinitis. Method: Twenty patients with moderate to severe persistent allergic rhinitis were enrolled in a randomized, double-blind, self-controlled study. The nasal cavity was lavaged with hydrogen-rich normal saline and normal saline,
Animal StudyHighlightedHydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stressMHID-5191051PMID: 281009592017Journal of InflammationShaoqing Yu, Chuanliang Zhao, Na Che, Lin Jing, Rongming GeBackground: It is well considered that reactive oxygen species (ROS) plays a prominent causative role in the development of allergic rhinitis (AR), and eosinophils cells as important allergic inflammatory cells contribute to elevating oxidative stress. Hydrogen, emerging as a novel antioxidant, has been proven effective in selectively reducing ROS in animals models of oxidative damage. We herein a
