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Showing 21–24 of 24 articles

Literature ReviewHighlighted

Hydrogen as a New Class of Radioprotective Agent

MHID-2487803PMID: 306788962013International Journal of Biological Sciences

Liren Qian, Jianliang Shen, Yunhai Chuai, Jianming Cai

It is well known that most of the ionizing radiation-induced damage is caused by hydroxyl radicals (·OH) follows radiolysis of H2O. Molecular hydrogen (H2) has antioxidant activities by selectively reducing ·OH and peroxynitrite(ONOO-). We firstly hypothesized and demonstrated the ra-dioprotective effect of H2 in vitro and in vivo, which was also repeated on different experimental animal models by

Animal StudyHighlighted

Histological Study on the Effect of Electrolyzed Reduced Water-Bathing on UVB Radiation-Induced Skin Injury in Hairless Mice

MHID-2488306PMID: 220408782011Biological & Pharmaceutical Bulletin

Kyung Su YOON, Xue Zhu HUANG, Yang Suk YOON, Soo-Ki Kim, Soon Bong SONG, Byung Soo CHANG, et al.

Electrolyzed reduced water (ERW), functional water, has various beneficial effects via antioxidant mecha- nism in vivo and in vitro. However there is no study about beneficial effects of ERW bathing. This study aimed to determine the effect of ERW bathing on the UVB-induced skin injury in hairless mice. For this purpose, mice were irradiated with UVB to cause skin injury, followed by individually ta

Human StudyLiterature ReviewAnimal StudyIn VitroHighlighted

The 2011 Medical Molecular Hydrogen Symposium: An inaugural symposium of the journal Medical Gas Research

MHID-1756030PMID: 221460822011Medical Gas Research

Shigeo Ohta, Atsunori Nakao, Kinji Ohno

This report summarizes a brief description/history of the Hydrogen Research Meetings as well as key presentations/oral abstracts delivered in the most recent symposium. Additionally, we introduced 38 diseases and physiological states for which hydrogen exhibits beneficial effects.

In VitroObservational Study

Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes

MHID-9621518PMID: 220709002011Journal of Photochemistry and Photobiology B: Biology

Shinya Kato, Yasukazu Saitoh, Keizou Iwai, Nobuhiko Miwa

Hydrogen-rich electrolyzed warm water (HW) was prepared at 41ºC and exhibited dissolved hydrogen (DH) of 1.13 ppm and an oxidation-reduction potential (ORP) of -741 mV in contrast to below 0.01 ppm and +184 mV for regular warm water (RW). Fibroblasts OUMS-36 and keratinocytes HaCaT were used to examine effects of HW against UVA-ray irradiation. Type-I collagen was synthesized 1.85- to 2.03-fold m