Literature ReviewHighlighted
MHID-4821613PMID: 339191462024Pul’monologiya
Alexander G. Chuchalin
The aim of the review was to examine the main characteristics of hydrogen ion metabolism and its hemostatic function in the human body. For diagnostic purposes, molecular hydrogen (H2) is considered a biological marker. The results of the analysis of therapeutic programs for the clinical use of hydrogen are presented. The use of H2 as a drug in the treatment of more than 170 diseases is also discu
Animal StudyIn VitroEx Vivo
MHID-0828029PMID: 397658042024Antioxidants
Deng-Yu Kuo, Yu-Chi Wang, Pei-Han Chou, Chen-Wei Lai, Fu-I Tung, Tse-Ying Liu
Radiation dermatitis (RD) is a common side effect in patients receiving radiotherapy. Currently, clinical skincare approaches for acute RD vary widely among institutions and lack consensus. Hydrogen molecules, acting as radioprotective agents by selectively scavenging free radicals, have the potential to protect against RD. In this study, we demonstrate that hydrogen reduces double- strand breaks,
In Vitro
MHID-0313161PMID: 340286462021Molecular and Cellular Biochemistry
Yasukazu Saitoh, Yuuki Yamaguchi, Yuhei Okada
Molecular hydrogen (H2) is recognized as a gaseous antioxidant, and it is expected to ameliorate various disorders related to oxidative stress and inflammation. However, there are still many unclear points regarding its effectiveness in the skin. Therefore, the purpose of this study was to examine the protective effect of H2 against ultraviolet (UV) irradiation-related stress injury in human epide
Observational StudyHighlighted
MHID-3602984PMID: 312492542019Medical Gas Research
Ryoko Asada, Yasukazu Saitoh, Nobuhiko Miwa
Hydrogen-dissolved water has been shown to improve diverse oxidation stress-related diseases, which drove us to examine effects of hydrogen-rich water on oxidation stress-related skin troubles and lipid-metabolism markers. The purpose of this study is whether the dissolved hydrogen in hydrogen-rich water was kept even after boiling, and whether hydrogen-bath utilization improves cosmetic effects s
Literature ReviewHighlighted
MHID-2847992PMID: 278264242016Medical Gas Research
Ou-yang Chen, Zhou-heng Ye, Chong Li
June 27, 2015, the Second Hydrogen Molecule Biomedical Symposium and the Second meeting of the Professional Committee of Molecular Hydrogen Biology and Medicine of China Association of Promoting International Communication of health care was grand opening in the Capital of China, Beijing, sponsored by China Association of Promoting International Communication of health care, undertaken by Professi
Animal StudyHighlighted
MHID-2488306PMID: 220408782011Biological & Pharmaceutical Bulletin
Kyung Su YOON, Xue Zhu HUANG, Yang Suk YOON, Soo-Ki Kim, Soon Bong SONG, Byung Soo CHANG, et al.
Electrolyzed reduced water (ERW), functional water, has various beneficial effects via antioxidant mecha-
nism in vivo and in vitro. However there is no study about beneficial effects of ERW bathing. This study aimed to
determine the effect of ERW bathing on the UVB-induced skin injury in hairless mice. For this purpose, mice
were irradiated with UVB to cause skin injury, followed by individually ta
In VitroObservational Study
MHID-9621518PMID: 220709002011Journal of Photochemistry and Photobiology B: Biology
Shinya Kato, Yasukazu Saitoh, Keizou Iwai, Nobuhiko Miwa
Hydrogen-rich electrolyzed warm water (HW) was prepared at 41ºC and exhibited dissolved hydrogen (DH) of 1.13 ppm and an oxidation-reduction potential (ORP) of -741 mV in contrast to below 0.01 ppm and +184 mV for regular warm water (RW).
Fibroblasts OUMS-36 and keratinocytes HaCaT were used to examine effects of HW against UVA-ray irradiation. Type-I collagen was synthesized 1.85- to 2.03-fold m
