Mechanisms ReviewHighlighted✓ Verified by MHI

Mesenchymal Stem Cell Priming: Potential Benefits of Administration of Molecular Hydrogen

Mikhail Yu. Artamonov, Tyler W. LeBaron, Felix A. Pyatakovich, Inessa A. Minenko

Pharmaceuticals · 2024 · 17(4) · 469

View PDF

Abstract

Stem cell therapy has emerged as a promising avenue for regenerative medicine, offering the potential to treat a wide range of debilitating diseases and injuries. Among the various types of stem cells, mesenchymal stem cells (MSCs) have garnered significant attention due to their unique properties and therapeutic potential. In recent years, researchers have been exploring novel approaches to enhance the effectiveness of MSC-based therapies. One such approach that has gained traction is the priming of MSCs with molecular hydrogen (H2). This article delves into the fascinating world of mesenchymal stem cell priming with molecular hydrogen and the potential benefits it holds for regenerative medicine.

Study details

Article type
Review
Disease / injury model
Not Applicable (Review)
Outcome
Positive
Findings
Priming mesenchymal stem cells (MSCs) with molecular hydrogen (H2) may enhance their therapeutic potential by reducing oxidative stress, inflammation, and cellular senescence, and improving immunomodulation and survival. This approach may improve outcomes in regenerative medicine, but optimal dosing and protocols require further research.

Classification

Organs & Tissues
Physiological Systems
Methods of Administration
Countries
Also
Highlighted Articles